In this example, the Vibro® Membrane Filtration (VMF) technology is used as perfusion device to retain cells in the bioreactor and to harvest API in the permeate from VMF1.
Description:
Use of VMF to treat bleed stream by harvesting API and removing up concentrated cells with less API loss.
Harvest/API can be up-concentrated using VMF and remove HCP and impurities to extend capture/Z1 column capacity and lifetime.
Similar setup can be applied to other cell-based applications (cultivated meat, cell therapy, etc.)