
Single-Pass VMF of mRNA
Single-Pass VMF significantly enhances the performance of in-line concentration and purification of mRNA constructs, with more than triple the sustainable flux rates reported for conventional single-pass TFF.

Single-Pass VMF significantly enhances the performance of in-line concentration and purification of mRNA constructs, with more than triple the sustainable flux rates reported for conventional single-pass TFF.

Precipitation combined with Single-Pass Vibro® Membrane Filtration (VMF) is an interesting alternative to Protein A chromatography for the continuous purification of precipitated mAbs.

Single-pass VMF outperforms conventional single-pass TFF in the concentration of mAbs, with minimal fouling, high concentration and conversion efficiency and gentle, stable operation.