Single-Pass VMF of Precipitated mAbs
Precipitation combined with Single-Pass Vibro® Membrane Filtration (VMF) is an interesting alternative to Protein A chromatography for the continuous purification of precipitated mAbs.
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Single-Pass VMF of mRNA
Single-Pass VMF significantly enhances the performance of in-line concentration and purification of mRNA constructs, with more than triple the sustainable flux rates reported for conventional single-pass TFF.
VMF of E. coli Cultures & Lysates
VMF performs better than conventional TFF for the processing of high‑density E. coli cultures and lysates, making it a robust, high-performance solution for demanding midstream applications.
Mass transfer characteristics of VMF Protein UF
VMF technology delivers a step change in protein ultrafiltration performance. It enables higher productivity, lower operating pressure and improved process robustness in bioprocessing, particularly for the concentration of monoclonal antibodies (mAbs) and other high‑value protein products.
Single-Pass VMF of mAbs
Single-pass VMF outperforms conventional single-pass TFF in the concentration of mAbs, with minimal fouling, high concentration and conversion efficiency and gentle, stable operation.
API/Protein Concentration & Recovery
In the following example, the Vibro® Technology is applied in an extracellular API/protein process where the fermentation broth is processed directly, and a…
Single-Step Cell Concentration & API Recovery
In this example, a fermentation broth containing cells such as E. coli bacteria is being harvested and concentrated directly from the harvest…
Concentration of Skim Milk to Greek Yoghurt
In the following example, the Vibro® Technology is applied to a Greek Yoghurt process where the cultured skim milk is concentrated to Greek…
Algae Harvest
In the following example, the Vibro® Membrane Filtration (VMF) technology is used for algae harvest and concentration. Description: Algae culture from a pond…