VMF clarification of E. coli & lysates
VMF outperforms conventional TFF in terms of process time, suspended solid
loading and target protein recovery in demanding midstream applications.
Resources
Mass transfer characteristics of VMF Protein UF
VMF technology delivers a step change in protein ultrafiltration performance. It enables higher productivity, lower operating pressure and improved process robustness in bioprocessing, particularly for the concentration of monoclonal antibodies (mAbs) and other high‑value protein products.
Single-Pass VMF mAbs
Single-Pass VMF outperforms conventional SPTFF with minimal fouling, high concentration efficiency, and gentle, stable operation. It enables true Single-Pass concentration in a single step — a breakthrough in continuous bioprocessing.
Single-Pass TFF mAbs
Continuous processing of mAbs with groundbreaking Vibro® technology.
Single-Pass Tangential Flow Filtration (SPTFF) with Vibro® Membrane Filtration (VMF)
Single-Pass TFF mRNA
Outstanding mRNA concentration by Vibro technology.
Higher flux without compromising conversion rates.
Filtration of Biologics in Continuous/Perfusion processes
In this example, the Vibro® Membrane Filtration (VMF) technology is used as perfusion device to retain cells in the bioreactor and to…
Harvest of Mammalian Cell Cultivations
In the following example, the Vibro® Membrane Filtration (VMF) technology is used for the critical solid/liquid separation following cultivation of mammalian cells. Description:…
API/Protein Concentration & Recovery
In the following example, the Vibro® Technology is applied in an extracellular API/protein process where the fermentation broth is processed directly, and a…
Concentration of E.Coli
In this example, the fermentation broth containing E. coli bacteria has been harvested and concentrated directly from the harvest tank using VMF…