NEXT GENERATION MICRO- & ULTRAFILTRATION

boosts process economy

By combining uniform TMP with vibration‑driven anti‑fouling, VMF enables optimal membrane utilization and stable filtration performance. This results in higher yield and recovery with a substantially smaller footprint and improved process economy.

Protects product quality

VMF uses localized vibrations to create targeted turbulence at the membrane surface only. This lowers overall system shear, protects sensitive cells and biomolecules and enables continuous processing.

scalable

Thanks to its modular build, VMF allows for a seamless, reliable scale-up from process development to full industrial production, supporting efficient tech transfer, reducing risk and accelerating scale-up.

“With vibration, we were able to get to a 40-fold concentration factor without any unstable transmembrane pressure.”

Andrew Zydney, Chair and Professor of Chemical Engineering, Penn State University

THE FUTURE OF FILTRATION is Vibro®

What if membrane filtration could deliver higher transmission, gentler processing, and dramatically reduced fouling — all in a simple, energy‑efficient design? Sani Membranes’ Vibro^® Membrane Filtration (VMF) redefines what’s possible in bioprocessing through its dynamic, vibration-based anti-fouling mechanism.

Explore the technology

”The Vibro-I filter is a robust solution, simple to use with no technical issues and with good flux. Power consumption under all operations (microfiltration / ultrafiltration) is much lower than in any other known filter technology.”

Science Manager at Novozymes

“…VMF has reduced fouling and concentration polarization, leading to increased filtration performance, without any negative effects on the biological products.”

Andrew Zydney, Chair and Professor of Chemical Engineering, Penn State University

big claims backed by real data

Our Vibro^® Membrane Filtration (VMF) technology is more than innovative—it’s independently validated across multiple applications. In peer-reviewed studies, VMF has demonstrated, among others:

• Up to 20× concentration in a single pass for proteins and mAbs, with robust, long-term operation and minimal fouling.
• Superior mRNA concentration, achieving high flux, high conversion, and preserving product integrity—even in continuous, 24-hour runs.
• Consistent, gentle processing that protects sensitive biomolecules and streamlines DSP, outperforming conventional TFF in both yield and process economy.

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ISO 9001:2015 Certified

This certification is a testament to our customer promise and dedication to deliver products that meet the highest standards in quality, reliability, and performance—every time.

INNOVATION made in denmark

Sani Membranes is more than just a technology provider—we’re a committed industry partner continuously rethinking and challenging what’s possible in micro‑ and ultrafiltration. With our disruptive Vibro^® technology and a unified team of specialists, we deliver solutions that elevate our customer’s processes and partner closely with them to solve problems others in the industry can’t.

Meet sani membranes