Category Articles

Factsheet about single-step filtration of precipitated mAbs using VMF

Single-Pass VMF of Precipitated mAbs

Precipitation combined with Single-Pass Vibro® Membrane Filtration (VMF) is an interesting alternative to Protein A chromatography for the continuous purification of precipitated mAbs.

Factsheet about single-step filtration of mRNA using VMF

Single-Pass VMF of mRNA

Single-Pass VMF significantly enhances the performance of in-line concentration and purification of mRNA constructs, with more than triple the sustainable flux rates reported for conventional single-pass TFF.

Factsheet about the VMF of E. coli cultures and lysates

VMF of E. coli Cultures & Lysates

VMF performs better than conventional TFF for the processing of high‑density E. coli cultures and lysates, making it a robust, high-performance solution for demanding midstream applications.

Article about the mass-transfer characteristics of VMF protein ultrafiltration

Mass transfer characteristics of VMF Protein UF

VMF technology delivers a step change in protein ultrafiltration performance. It enables higher productivity, lower operating pressure and improved process robustness in bioprocessing, particularly for the concentration of monoclonal antibodies (mAbs) and other high‑value protein products.

Factsheet about single-step filtration of mAbs using VMF

Single-Pass VMF of mAbs

Single-pass VMF outperforms conventional single-pass TFF in the concentration of mAbs, with minimal fouling, high concentration and conversion efficiency and gentle, stable operation.