In this example, the Vibro® Membrane Filtration (VMF) technology is used as perfusion device to retain cells in the bioreactor and to harvest API in the permeate from VMF1. Description: Use of VMF to treat bleed stream by harvesting API…
In the following example, the Vibro® Membrane Filtration (VMF) technology is used for the critical solid/liquid separation following cultivation of mammalian cells. Description: Vibro® technology has proven to be an effective means of cell removal from cultivation broth, both in microbial and…
In the following example, the Vibro® Technology is applied in an extracellular API/protein process where the fermentation broth is processed directly, and a concentrated API/protein is achieved. Description: The fermentation broth is processed in a Vibro-I microfiltration unit where the cells are separated…
In this example, the fermentation broth containing E. coli bacteria has been harvested and concentrated directly from the harvest tank using VMF technology. Description: VMF is characterized by having very low flow resistance and being capable of uniform TMP, while…
In this example, VMF is used for an extracellular clarification process, where the fermentation broth is processed directly to a clear, and a cleaned API/protein is achieved. Description: Due to the unique VMF technology, this setup can also be used…
In the following example, the Vibro® Technology is applied to a Greek Yoghurt process where the cultured skim milk is concentrated to Greek Yoghurt. Description: The cultured milk is processed in a Vibro-I unit with 3 steps. The first step is…
In the following example, the Vibro® Membrane Filtration (VMF) technology is used for algae harvest and concentration. Description: Algae culture from a pond or a photo bioreactor is processed continuously or as batch with plug flow through a Vibro-I preconcentration system…
In the following example, the Vibro® Membrane Filtration (VMF) technology is used for cell culture process intensification. Description:
In this example, VMF is applied in brewery operations, where it has the potential to be used in a range of applications and can replace a variety of conventional technologies such as High Speed Separators (HSS), with both qualitative and…